BGH

These exosomes are nanoscale vesicles released by cells, rich in proteins, nucleic acids, and lipids, which facilitate intercellular communication. Exosomes have advantages such as low immunogenicity, reduced risk of rejection, and the ability to cross the blood-brain barrier, making them a promising therapeutic strategy for neurodegenerative diseases like Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis (ALS). Studies have shown that stem cell-derived exosomes can slow disease progression through multiple mechanisms, including anti-inflammatory effects, neuroprotection, neural repair, and immune regulation. Additionally, the microRNAs (miRNAs) contained within exosomes can influence neuronal survival and synaptic plasticity, further enhancing neuroregeneration. Exosomes hold great promise as a novel biotherapeutic tool for neurodegenerative diseases, potentially improving patients’ quality of life.We will explore the use of different types of stem cells and exosomes derived from their differentiation into neural-like cells for research. Our goal is to evaluate the therapeutic potential of these exosomes from various sources for neurological diseases and identify the most suitable exosome type for further drug development.